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IMAB027
🥰Excellent
Catalog No. T78296Cas No. 1650599-68-0
Alias IMAB 027, ASP-1650, ASP1650, ASP 1650
IMAB027 (ASP1650) is a selective monoclonal antibody against CLDN6 (Claudin 6) with antitumor activity that induces death of CLDN6+ cancer cells through antibody-dependent and complement-dependent cytotoxicity.
IMAB027
IMAB027
🥰Excellent
Purity: 95%
Catalog No. T78296Alias IMAB 027, ASP-1650, ASP1650, ASP 1650Cas No. 1650599-68-0
IMAB027 (ASP1650) is a selective monoclonal antibody against CLDN6 (Claudin 6) with antitumor activity that induces death of CLDN6+ cancer cells through antibody-dependent and complement-dependent cytotoxicity.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $298 | In Stock | |
| 5 mg | $723 | In Stock | |
| 10 mg | $975 | In Stock | |
| 25 mg | $1,430 | In Stock | |
| 50 mg | $1,950 | In Stock |
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Concentration:6.59 mg/mL
Purity:95%
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Product Introduction
Bioactivity
Chemical Properties
| Description | IMAB027 (ASP1650) is a selective monoclonal antibody against CLDN6 (Claudin 6) with antitumor activity that induces death of CLDN6+ cancer cells through antibody-dependent and complement-dependent cytotoxicity. |
| In vitro | IMAB027 selectively binds to CLDN6 but not to its closely related family members such as Claudins 3, 4 and 9. In CLDN6+-expressing ovarian and testicular cancer cell lines, IMAB027 was able to induce selective antibody-dependent cell-mediated cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC) in target cells. [1] |
| In vivo | IMAB027 inhibited tumor growth and improved overall survival in mice transplanted with human CLDN6+ cells. [1] |
| Alias | IMAB 027, ASP-1650, ASP1650, ASP 1650 |
| Cas No. | 1650599-68-0 |
Storage & Solubility Information
| Storage | store at low temperature | store at -20°C | Shipping with blue ice. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Related Tags: buy IMAB027 | purchase IMAB027 | IMAB027 cost | order IMAB027 | IMAB027 in vivo | IMAB027 in vitro
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