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Inogatran is a synthetic thrombin inhibitor, developed for the possible treatment and prophylaxis of venous and arterial thrombotic diseases.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $2,120 | 8-10 weeks | |
50 mg | $2,780 | 8-10 weeks | |
100 mg | $3,700 | 8-10 weeks |
Description | Inogatran is a synthetic thrombin inhibitor, developed for the possible treatment and prophylaxis of venous and arterial thrombotic diseases. |
In vivo | Inogatran enhances vena caval blood circulation and diminishes the frequency of thrombotic occlusions in rat studies. Administered intravenously in a canine model of venous thrombosis at dosages of 0.075, 0.25, and 0.75 mg/kg, Inogatran (H-314-27) exhibits a dose-dependent augmentation in activated partial thromboplastin time (aPTT), thrombin time (TT), and prothrombin time (PT), indicative of its anticoagulant effects. This corresponds with a dose-related inhibition of thrombus formation, evidenced by extended time to occlusion (TTO) and reduced thrombus mass. |
Alias | H-314-27 |
Molecular Weight | 438.56 |
Formula | C21H38N6O4 |
Cas No. | 155415-08-0 |
Relative Density. | 1.36g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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