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Irisquinone

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Catalog No. T82046Cas No. 56495-82-0

Irisquinone, a natural anticancer agent, also acts as a radiation sensitizer for cancer therapies. It diminishes glutathione (GSH) levels and hampers the repair of single-strand DNA breaks [1] [2] [3].

Irisquinone

Irisquinone

😃Good
Catalog No. T82046Cas No. 56495-82-0
Irisquinone, a natural anticancer agent, also acts as a radiation sensitizer for cancer therapies. It diminishes glutathione (GSH) levels and hampers the repair of single-strand DNA breaks [1] [2] [3].
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Product Introduction

Bioactivity
Description
Irisquinone, a natural anticancer agent, also acts as a radiation sensitizer for cancer therapies. It diminishes glutathione (GSH) levels and hampers the repair of single-strand DNA breaks [1] [2] [3].
In vitro
Irisquinone (0-128 nM, 12-48 h) induces apoptosis in rat C6 glioma cells [2].
In vivo
Irisquinone (12.5 mg/kg, daily administration) induced a reduction in tumor wall thickness and an increase in necrotic area in rabbits with VX2 lung transplant tumor models when combined with radiotherapy [1].
Chemical Properties
Molecular Weight374.56
FormulaC24H38O3
Cas No.56495-82-0
Storage & Solubility Information
StorageShipping with blue ice.

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