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Isoglobotriaose

Name: Isoglobotriaose
Brand: TargetMol
SKU: T82032
Price: 29 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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Catalog No. T82032Cas No. 41744-59-6

Alias Gala-3Galb-4Glc

Isoglobotriaose (Gala-3Galb-4Glc), a mammalian tissue glycosphingolipid, is a Globotriaose analogue. The ganglioside derivatives of Isoglobotriaose and Globotriaose differ in their small intestine distribution: isoglobotriaosylceramide localizes exclusively to the non-epithelial residue, whereas globotriaosylceramide is present in both compartments [1] [2].

Isoglobotriaose

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Catalog No. T82032Alias Gala-3Galb-4GlcCas No. 41744-59-6

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Product Introduction

Bioactivity

Description	Isoglobotriaose (Gala-3Galb-4Glc), a mammalian tissue glycosphingolipid, is a Globotriaose analogue. The ganglioside derivatives of Isoglobotriaose and Globotriaose differ in their small intestine distribution: isoglobotriaosylceramide localizes exclusively to the non-epithelial residue, whereas globotriaosylceramide is present in both compartments [1] [2].
In vitro	Isoglobotriaose is produced through a one-pot enzymatic synthesis involving lactose, glucose-1-phosphate (Glc-1-P), and uridine 5'-triphosphate (UTP). This reaction system employs three enzymes: UDP-glucose pyrophosphorylase (GlaU), UDP-Gal 4-epimerase (GalE), and α1-3 galactosyltransferase (α1-3GalT)[1].
Alias	Gala-3Galb-4Glc

Chemical Properties

Molecular Weight	504.44
Formula	C₁₈H₃₂O₁₆
Cas No.	41744-59-6

Storage & Solubility Information

Storage

Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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