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Isoglobotriaose

Name: Isoglobotriaose
Brand: TargetMol
SKU: T82032
Price: 47 USD
Availability: InStock
Rating: 4.5 (1 reviews)

Catalog No. T82032Cas No. 41744-59-6

Alias Gala-3Galb-4Glc

Isoglobotriaose (Gala-3Galb-4Glc), a mammalian tissue glycosphingolipid, is a Globotriaose analogue. The ganglioside derivatives of Isoglobotriaose and Globotriaose differ in their small intestine distribution: isoglobotriaosylceramide localizes exclusively to the non-epithelial residue, whereas globotriaosylceramide is present in both compartments [1] [2].

Isoglobotriaose

Catalog No. T82032Alias Gala-3Galb-4GlcCas No. 41744-59-6

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Product Introduction

Bioactivity

Description	Isoglobotriaose (Gala-3Galb-4Glc), a mammalian tissue glycosphingolipid, is a Globotriaose analogue. The ganglioside derivatives of Isoglobotriaose and Globotriaose differ in their small intestine distribution: isoglobotriaosylceramide localizes exclusively to the non-epithelial residue, whereas globotriaosylceramide is present in both compartments [1] [2].
In vitro	Isoglobotriaose is produced through a one-pot enzymatic synthesis involving lactose, glucose-1-phosphate (Glc-1-P), and uridine 5'-triphosphate (UTP). This reaction system employs three enzymes: UDP-glucose pyrophosphorylase (GlaU), UDP-Gal 4-epimerase (GalE), and α1-3 galactosyltransferase (α1-3GalT)[1].
Alias	Gala-3Galb-4Glc

Chemical Properties

Molecular Weight	504.44
Formula	C₁₈H₃₂O₁₆
Cas No.	41744-59-6

Storage & Solubility Information

Storage

Shipping with blue ice.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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