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NSC 694621

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Catalog No. T60018Cas No. 104857-29-6

NSC 694621 is a potent PCAF inhibitor with an IC50 of 5.71 μM (PCAF/H3 1-21) and demonstrates significant activity in inhibiting cancer cell proliferation, indicating potential as a new anticancer agent[1].

NSC 694621

NSC 694621

😃Good
Catalog No. T60018Cas No. 104857-29-6
NSC 694621 is a potent PCAF inhibitor with an IC50 of 5.71 μM (PCAF/H3 1-21) and demonstrates significant activity in inhibiting cancer cell proliferation, indicating potential as a new anticancer agent[1].
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2 mg$585 days
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Product Introduction

Bioactivity
Description
NSC 694621 is a potent PCAF inhibitor with an IC50 of 5.71 μM (PCAF/H3 1-21) and demonstrates significant activity in inhibiting cancer cell proliferation, indicating potential as a new anticancer agent[1].
In vitro
NSC 694621 (25 μM; 72 h) exhibits the effect of antiproliferative to SK-N-SH and HCT116 cells [1]. Cell Proliferation Assay [1] Cell Line: SK-N-SH, HCT116 cells Concentration: 25 μM Incubation Time: 72 h Result: Showed antiproliferative effect to SK-N-SH and HCT116 cells with GI 50 of 19.2 μM and growth inhibition of 29%, respectively.
Chemical Properties
Molecular Weight258.3
FormulaC13H10N2O2S
Cas No.104857-29-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

NSC 694621NSC-694621NSC694621Isothiazolo[5,4 b]pyridin 3(2H) one, 2 (4 methoxyphenyl) Isothiazolo[5,4b]pyridin3(2H)one, 2(4methoxyphenyl)
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