Shopping Cart
- Remove All
Your shopping cart is currently empty
ITF5924
ITF5924 (compound 1), a potent HDAC6 inhibitor featuring a difluoromethyl-1,3,4-oxadiazole (DFMO) moiety, exhibits an IC 50 of 7.7 nM and surpasses 104-fold selectivity over other HDAC subtypes. As a slow-binding substrate analog of HDAC6, ITF5924 undergoes an enzyme-catalyzed ring opening reaction, resulting in the formation of a stable, long-lasting enzyme-inhibitor complex [1].
Catalog No. T86748Cas No. 2760854-72-4
Contact us for more batch information
Resource Download
ITF5924
Catalog No. T86748Cas No. 2760854-72-4
ITF5924 (compound 1), a potent HDAC6 inhibitor featuring a difluoromethyl-1,3,4-oxadiazole (DFMO) moiety, exhibits an IC 50 of 7.7 nM and surpasses 104-fold selectivity over other HDAC subtypes. As a slow-binding substrate analog of HDAC6, ITF5924 undergoes an enzyme-catalyzed ring opening reaction, resulting in the formation of a stable, long-lasting enzyme-inhibitor complex [1].
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks |
Bulk & Custom
Add to Cart
Questions
View MoreProduct Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | ITF5924 (compound 1), a potent HDAC6 inhibitor featuring a difluoromethyl-1,3,4-oxadiazole (DFMO) moiety, exhibits an IC 50 of 7.7 nM and surpasses 104-fold selectivity over other HDAC subtypes. As a slow-binding substrate analog of HDAC6, ITF5924 undergoes an enzyme-catalyzed ring opening reaction, resulting in the formation of a stable, long-lasting enzyme-inhibitor complex [1]. |
| Targets&IC50 | HDAC6:7.7 nM |
| Molecular Weight | 436.42 |
| Formula | C21H18F2N8O |
| Cas No. | 2760854-72-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy ITF5924 | purchase ITF5924 | ITF5924 cost | order ITF5924 | ITF5924 chemical structure | ITF5924 formula | ITF5924 molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.