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JAK-IN-19

Catalog No. T63026

JAK-IN-19 is a potent JAK inhibitor with pIC50 values of 7.2 for PBMC (IFNγ) and 7.7 for HLF (Eotaxin). The compound also exhibits pIC50 values of 7.0 for VEGFR2 and 5.8 for Aurora B.

JAK-IN-19

JAK-IN-19

Catalog No. T63026
JAK-IN-19 is a potent JAK inhibitor with pIC50 values of 7.2 for PBMC (IFNγ) and 7.7 for HLF (Eotaxin). The compound also exhibits pIC50 values of 7.0 for VEGFR2 and 5.8 for Aurora B.
Pack SizePriceAvailabilityQuantity
25 mg$1,52010-14 weeks
50 mg$1,98010-14 weeks
100 mg$2,50010-14 weeks
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Product Introduction

Bioactivity
Description
JAK-IN-19 is a potent JAK inhibitor with pIC50 values of 7.2 for PBMC (IFNγ) and 7.7 for HLF (Eotaxin). The compound also exhibits pIC50 values of 7.0 for VEGFR2 and 5.8 for Aurora B.
Chemical Properties
Molecular Weight469.59
FormulaC26H36FN5O2
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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