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JPS016

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Catalog No. T74454Cas No. 2669785-77-5

JPS016, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), effectively degrades class I histone deacetylase (HDAC). It serves as a potent HDAC1/2 degrader, resulting in a significant increase in differentially expressed genes and enhanced apoptosis in HCT116 cells [1].

JPS016
Other Forms of JPS016:
JPS016 TFAT77938
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JPS016

😃Good
Catalog No. T74454Cas No. 2669785-77-5
JPS016, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), effectively degrades class I histone deacetylase (HDAC). It serves as a potent HDAC1/2 degrader, resulting in a significant increase in differentially expressed genes and enhanced apoptosis in HCT116 cells [1].
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Product Introduction

Bioactivity
Description
JPS016, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), effectively degrades class I histone deacetylase (HDAC). It serves as a potent HDAC1/2 degrader, resulting in a significant increase in differentially expressed genes and enhanced apoptosis in HCT116 cells [1].
Chemical Properties
Molecular Weight898.12
FormulaC48H63N7O8S
Cas No.2669785-77-5
Storage & Solubility Information
StorageShipping with blue ice.

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