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JPS036

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Catalog No. T74456Cas No. 2669785-85-5

JPS036, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), efficiently degrades class I histone deacetylase (HDAC), particularly HDAC1/2. Its activity results in a substantial increase in differentially expressed genes and promotes enhanced apoptosis in HCT116 cells [1].

JPS036

JPS036

😃Good
Catalog No. T74456Cas No. 2669785-85-5
JPS036, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), efficiently degrades class I histone deacetylase (HDAC), particularly HDAC1/2. Its activity results in a substantial increase in differentially expressed genes and promotes enhanced apoptosis in HCT116 cells [1].
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Product Introduction

Bioactivity
Description
JPS036, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), efficiently degrades class I histone deacetylase (HDAC), particularly HDAC1/2. Its activity results in a substantial increase in differentially expressed genes and promotes enhanced apoptosis in HCT116 cells [1].
Chemical Properties
Molecular Weight940.18
FormulaC51H66FN7O7S
Cas No.2669785-85-5
Storage & Solubility Information
StorageShipping with blue ice.

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