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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | Keap1-Nrf2-IN-9 (compound 11) is a potent inhibitor of the Keap1-Nrf2 protein−protein interaction (PPI) with an IC50 value of 0.575 µM. It enhances the expression of Nrf2 target genes, including heme oxygenase 1 (Hmox1), glutathione S-transferase P (GstP), and glutamate-cysteine ligase catalytic (Gclc) and modulatory (Gclm) subunits. Notably, Keap1-Nrf2-IN-9 is not cytotoxic to ARPE19 cells [1]. |
Molecular Weight | 670.71 |
Formula | C31H30N2O11S2 |
Cas No. | 2769963-24-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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