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KF15766

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Catalog No. T89515Cas No. 124907-44-4

KF15766 (compd 34E) is an orally active dual antagonist of TXA2 and H1, with Kis of 740 nM and 20 nM, respectively. This compound is utilized in antiallergy research.

KF15766

KF15766

😃Good
Catalog No. T89515Cas No. 124907-44-4
KF15766 (compd 34E) is an orally active dual antagonist of TXA2 and H1, with Kis of 740 nM and 20 nM, respectively. This compound is utilized in antiallergy research.
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Product Introduction

Bioactivity
Description
KF15766 (compd 34E) is an orally active dual antagonist of TXA2 and H1, with Kis of 740 nM and 20 nM, respectively. This compound is utilized in antiallergy research.
In vivo
KF15766 (0.3, 10 mg/kg, p.o.) prevents bronchoconstriction in guinea pigs induced by histamine and U-46619.
Chemical Properties
Molecular Weight511.62
FormulaC30H31NO3.1/2C4H4O4
Cas No.124907-44-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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