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KRAS inhibitor-18

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Catalog No. T62784Cas No. 2230873-66-0

KRAS inhibitor-18 (compound 3-10) is a potent inhibitor of KRAS G12C (IC50: 4.74 μM) and exhibited p-ERK inhibition in MIA PaCA-2 and A549 cells with IC50s of 66.4 μM and 11.1 μM, respectively. KRAS inhibitor-18 has potential for pancreatic, colorectal, and lung cancer studies.

KRAS inhibitor-18

KRAS inhibitor-18

😃Good
Catalog No. T62784Cas No. 2230873-66-0
KRAS inhibitor-18 (compound 3-10) is a potent inhibitor of KRAS G12C (IC50: 4.74 μM) and exhibited p-ERK inhibition in MIA PaCA-2 and A549 cells with IC50s of 66.4 μM and 11.1 μM, respectively. KRAS inhibitor-18 has potential for pancreatic, colorectal, and lung cancer studies.
Pack SizePriceAvailabilityQuantity
25 mg1.444 €8-10 weeks
50 mg1.881 €8-10 weeks
100 mg2.375 €8-10 weeks
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Product Introduction

Bioactivity
Description
KRAS inhibitor-18 (compound 3-10) is a potent inhibitor of KRAS G12C (IC50: 4.74 μM) and exhibited p-ERK inhibition in MIA PaCA-2 and A549 cells with IC50s of 66.4 μM and 11.1 μM, respectively. KRAS inhibitor-18 has potential for pancreatic, colorectal, and lung cancer studies.
Chemical Properties
Molecular Weight453.87
FormulaC20H15ClF3N3O2S
Cas No.2230873-66-0
Storage & Solubility Information
StorageShipping with blue ice.

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