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KRH102053

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Catalog No. T70903Cas No. 1353254-53-1

KRH102053 is a HIF-1alpha inhibitor. KRH102053 decreased the protein level of HIF-1alpha and the mRNA levels of HIF-regulated downstream target genes, such as vascular endothelial growth factor, aldolase A, enolase 1 and monocarboxylate transporter 4. Consistent with these results, KRH102053 also inhibited the rates of HIF-related migration and invasion of HOS cells as well as the degree of tube formation in human umbilical vein endothelium cells.

KRH102053

KRH102053

😃Good
Catalog No. T70903Cas No. 1353254-53-1
KRH102053 is a HIF-1alpha inhibitor. KRH102053 decreased the protein level of HIF-1alpha and the mRNA levels of HIF-regulated downstream target genes, such as vascular endothelial growth factor, aldolase A, enolase 1 and monocarboxylate transporter 4. Consistent with these results, KRH102053 also inhibited the rates of HIF-related migration and invasion of HOS cells as well as the degree of tube formation in human umbilical vein endothelium cells.
Pack SizePriceAvailabilityQuantity
25 mg1.444 â‚¬6-8 weeks
50 mg1.881 â‚¬6-8 weeks
100 mg2.375 â‚¬6-8 weeks
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Product Introduction

Bioactivity
Description
KRH102053 is a HIF-1alpha inhibitor. KRH102053 decreased the protein level of HIF-1alpha and the mRNA levels of HIF-regulated downstream target genes, such as vascular endothelial growth factor, aldolase A, enolase 1 and monocarboxylate transporter 4. Consistent with these results, KRH102053 also inhibited the rates of HIF-related migration and invasion of HOS cells as well as the degree of tube formation in human umbilical vein endothelium cells.
Chemical Properties
Molecular Weight474.61
FormulaC25H34N2O5S
Cas No.1353254-53-1
Storage & Solubility Information
StorageShipping with blue ice.

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