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L-Ascorbic acid 2-phosphate
🥰Excellent
Catalog No. T19390Cas No. 23313-12-4
Alias 2-Phospho-L-ascorbic acid
L-ascorbic acid 2-phosphate (Vitamin C phosphate) is a stable and long-lasting vitamin C derivative that stimulates collagen formation and has potential antioxidant capacity. L-ascorbic acid 2-phosphate is commonly used to promote osteogenic differentiation of human adipose stem cells (hASCs) in cell culture by increasing alkaline phosphatase (ALP) activity and runt-related transcription factor-2-DNA(runx2A) expression.
L-Ascorbic acid 2-phosphate
🥰Excellent
Catalog No. T19390Alias 2-Phospho-L-ascorbic acidCas No. 23313-12-4
L-ascorbic acid 2-phosphate (Vitamin C phosphate) is a stable and long-lasting vitamin C derivative that stimulates collagen formation and has potential antioxidant capacity. L-ascorbic acid 2-phosphate is commonly used to promote osteogenic differentiation of human adipose stem cells (hASCs) in cell culture by increasing alkaline phosphatase (ALP) activity and runt-related transcription factor-2-DNA(runx2A) expression.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 200 mg | $30 | In Stock | |
| 500 mg | $43 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | L-ascorbic acid 2-phosphate (Vitamin C phosphate) is a stable and long-lasting vitamin C derivative that stimulates collagen formation and has potential antioxidant capacity. L-ascorbic acid 2-phosphate is commonly used to promote osteogenic differentiation of human adipose stem cells (hASCs) in cell culture by increasing alkaline phosphatase (ALP) activity and runt-related transcription factor-2-DNA(runx2A) expression. |
| Targets&IC50 | ALP: |
| In vitro | L-Ascorbic acid 2-phosphate (0.1-1.5 mM, every 2-3 days for 2-3 weeks) significantly stimulated cell growth, whereas addition of L-ascorbic acid (Asc) only achieved weak growth stimulation. [1] L-Ascorbic acid 2-phosphate (50 μM-250 μM) is required for efficient osteogenic differentiation of human adipose-derived stem cells (hASCs), and higher concentrations of AsA2-P lead to increased runx2 expression and ALP activity. [3] |
| Alias | 2-Phospho-L-ascorbic acid |
| Molecular Weight | 256.1 |
| Formula | C6H9O9P |
| Cas No. | 23313-12-4 |
| Smiles | O(P(=O)(O)O)C1=C(O)[C@@]([C@H](CO)O)(OC1=O)[H] |
| Relative Density. | 2.01 g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | H2O: < 0.1(insoluble) 1 M HCL: 20 mg/mL (78.09 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
1 M HCL
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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