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L-Homopropargylglycine hydrochloride is an alkyl-based PROTAC linker used in PROTAC synthesis. It is an amino acid analog of methionine with an alkyne group, enabling a click chemical reaction with azide-containing Alexa Fluor.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $78 | 35 days | |
10 mg | $125 | 35 days | |
50 mg | $460 | 35 days | |
100 mg | $595 | 35 days |
Description | L-Homopropargylglycine hydrochloride is an alkyl-based PROTAC linker used in PROTAC synthesis. It is an amino acid analog of methionine with an alkyne group, enabling a click chemical reaction with azide-containing Alexa Fluor. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 163.6 |
Formula | C6H10ClNO2 |
Cas No. | 942518-19-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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