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Laurolitsine hydrochloride (5890-18-6 free base)

Catalog No. T19403

Laurolitsine hydrochloride, shows weak anti-inflammatory activity,is an alkaloid isolated from Phoebe formosana.

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Pack Size	Price	Availability
1 mg	$135	Backorder
5 mg	$460	Backorder
10 mg	$812	Backorder
50 mg	Inquiry	Backorder
100 mg	Inquiry	Backorder
1 mL x 10 mM (in DMSO)	$475	Backorder

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Product Introduction

Bioactivity

Description	Laurolitsine hydrochloride, shows weak anti-inflammatory activity,is an alkaloid isolated from Phoebe formosana.
In vitro	Boldine, laurolitsine and litebamine (300 μM) remarkedly inhibit the aggregation of rabbit platelets induced by arachidonic acid (100 μM) and collagen (10 μM/mL), and slightly inhibit that induced by ADP (20 μM).Laurolitsine shows weak anti-inflammatory activity against NO production in RAW 267.4 and BV-2 cells.
Alias	(+)-Norboldine hydrochloride, Laurolitsine hydrochloride

Chemical Properties

Molecular Weight	349.81
Formula	C18H20ClNO4
Cas No.

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 83 mg/mL (237.27 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8587 mL	14.2935 mL	28.5869 mL	142.9347 mL
5 mM	0.5717 mL	2.8587 mL	5.7174 mL	28.5869 mL
10 mM	0.2859 mL	1.4293 mL	2.8587 mL	14.2935 mL
20 mM	0.1429 mL	0.7147 mL	1.4293 mL	7.1467 mL
50 mM	0.0572 mL	0.2859 mL	0.5717 mL	2.8587 mL
100 mM	0.0286 mL	0.1429 mL	0.2859 mL	1.4293 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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