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Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 mg | Inquiry | 7-10 days | |
100 mg | Inquiry | 7-10 days |
Description | Lenalidomide-4-OH is a cereblon (CRBN) ligand derived from Lenalidomide, utilized in the recruitment of the CRBN protein. It can be conjugated to the protein ligand via a linker, facilitating the formation of PROTAC. |
In vitro | PROTACs, consisting of two distinct ligands connected by a linker—one for an E3 ubiquitin ligase and the other for the target protein—utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
Molecular Weight | 260.25 |
Formula | C13H12N2O4 |
Cas No. | 1061604-41-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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