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Lenalidomide-4-OH

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Catalog No. T38457Cas No. 1061604-41-8

Lenalidomide-4-OH is a cereblon (CRBN) ligand derived from Lenalidomide, utilized in the recruitment of the CRBN protein. It can be conjugated to the protein ligand via a linker, facilitating the formation of PROTAC.

Lenalidomide-4-OH

Lenalidomide-4-OH

😃Good
Catalog No. T38457Cas No. 1061604-41-8
Lenalidomide-4-OH is a cereblon (CRBN) ligand derived from Lenalidomide, utilized in the recruitment of the CRBN protein. It can be conjugated to the protein ligand via a linker, facilitating the formation of PROTAC.
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50 mgInquiry7-10 days
100 mgInquiry7-10 days
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Product Introduction

Bioactivity
Description
Lenalidomide-4-OH is a cereblon (CRBN) ligand derived from Lenalidomide, utilized in the recruitment of the CRBN protein. It can be conjugated to the protein ligand via a linker, facilitating the formation of PROTAC.
In vitro
PROTACs, consisting of two distinct ligands connected by a linker—one for an E3 ubiquitin ligase and the other for the target protein—utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].
Chemical Properties
Molecular Weight260.25
FormulaC13H12N2O4
Cas No.1061604-41-8
Relative Density.1.498 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Keywords

Lenalidomide 4 OHLenalidomide-4-OHLenalidomide4OH
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