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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $44 | 5 days |
Description | Lenalidomide-C4-NH2 hydrochloride is a Cereblon ligand derived from Lenalidomide. It serves as a recruiting agent for the CRBN protein. The compound, known as PROTAC (Compound 24), can be formed by linking Lenalidomide-C4-NH2 hydrochloride to the ligand for the protein. It exhibits inhibitory effects with IC50s of 0.98 nM and 13.7 nM against the growth of RS4;11 and MOLM-13 acute leukemia cell lines, respectively[1]. |
Alias | Cereblon ligand 1 hydrochloride, E3 ligase Ligand-Linker Conjugates 32 hydrochloride |
Molecular Weight | 351.83 |
Formula | C17H22ClN3O3 |
Cas No. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 130 mg/mL (369.50 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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