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Lenalidomide-I (Compound 72) is a derivative of the cereblon (CRBN) ligand, Lenalidomide, with affinity for E3 ubiquitin ligase. It facilitates the recruitment of CRBN protein. Lenalidomide-I can be utilized in PROTACs, such as the PROTAC BET degrader QCA570, by linking it to the targeted protein ligand through a linker.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 mg | Inquiry | 7-10 days | |
100 mg | Inquiry | 7-10 days |
Description | Lenalidomide-I (Compound 72) is a derivative of the cereblon (CRBN) ligand, Lenalidomide, with affinity for E3 ubiquitin ligase. It facilitates the recruitment of CRBN protein. Lenalidomide-I can be utilized in PROTACs, such as the PROTAC BET degrader QCA570, by linking it to the targeted protein ligand through a linker. |
In vitro | Lenalidomide-I can be linked to a protein ligand via a linker to create PROTACs, which are agents that induce the ubiquitination-mediated degradation of proteins that promote cancer[1]. |
Molecular Weight | 370.14 |
Formula | C13H11IN2O3 |
Cas No. | 2207541-30-6 |
Relative Density. | 1.876 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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