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Leu-AMS R enantiomer

Name: Leu-AMS R enantiomer
Brand: TargetMol
SKU: T11841
Price: 34 USD
Availability: InStock
Rating: 4.5 (1 reviews)

Catalog No. T11841Cas No. 2580391-91-7

Leu-AMS (R enantiomer) is the R enantiomer of Leu-AMS, a potent leucyl-tRNA synthetase (LRS) inhibitor that inhibits bacterial growth.

Leu-AMS R enantiomer

Catalog No. T11841Cas No. 2580391-91-7

Leu-AMS (R enantiomer) is the R enantiomer of Leu-AMS, a potent leucyl-tRNA synthetase (LRS) inhibitor that inhibits bacterial growth.

Pack Size	Price	Availability	Quantity
25 mg	$1,500	10-14 weeks

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Product Introduction

Bioactivity

Description

Leu-AMS (R enantiomer) is the R enantiomer of Leu-AMS, a potent leucyl-tRNA synthetase (LRS) inhibitor that inhibits bacterial growth.

Chemical Properties

Molecular Weight	459.48
Formula	C₁₆H₂₅N₇O₇S
Cas No.	2580391-91-7

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 50.5 mg/mL (109.91 mM), Sonication and heating are recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1764 mL	10.8819 mL	21.7637 mL	108.8187 mL
5 mM	0.4353 mL	2.1764 mL	4.3527 mL	21.7637 mL
10 mM	0.2176 mL	1.0882 mL	2.1764 mL	10.8819 mL
20 mM	0.1088 mL	0.5441 mL	1.0882 mL	5.4409 mL
50 mM	0.0435 mL	0.2176 mL	0.4353 mL	2.1764 mL
100 mM	0.0218 mL	0.1088 mL	0.2176 mL	1.0882 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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