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Licoisoflavone B

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Catalog No. TN1864Cas No. 66056-30-2

Licoisoflavone B is an isoflavonoid from Glycyrrhiza uralensis Fisch.Licoisoflavone B inhibits lipid peroxidation and inhibits human cytochrome P450 enzymes (CYP2C8 and CYP2C9).

Licoisoflavone B

Licoisoflavone B

🥰Excellent
Catalog No. TN1864Cas No. 66056-30-2
Licoisoflavone B is an isoflavonoid from Glycyrrhiza uralensis Fisch.Licoisoflavone B inhibits lipid peroxidation and inhibits human cytochrome P450 enzymes (CYP2C8 and CYP2C9).
Pack SizePriceAvailabilityQuantity
1 mg$283In Stock
5 mg$698In Stock
10 mg$993In Stock
25 mg$1,470In Stock
50 mg$1,990In Stock
1 mL x 10 mM (in DMSO)$865In Stock
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Product Introduction

Bioactivity
Description
Licoisoflavone B is an isoflavonoid from Glycyrrhiza uralensis Fisch.Licoisoflavone B inhibits lipid peroxidation and inhibits human cytochrome P450 enzymes (CYP2C8 and CYP2C9).
In vitro
We present the results of an in vitro investigation of the inhibitory effects of licoisoflavone A and Licoisoflavone B and sophoraisoflavone A isolated from Sophra mooracroftiana BETH ex BAKER on copper-induced protein oxidative modification of mice brain homogenate in vitro. Although inhibitory effect of sophoraisoflavone A was stronger than those of licoisoflavone A and Licoisoflavone B, genistein as a related isoflavone, and mannitol as a hydroxy radical scavenger, inhibitory effects of licoisoflavone A and Licoisoflavone B were weaker than those of genistein and mannitol[1]
Chemical Properties
Molecular Weight352.34
FormulaC20H16O6
Cas No.66056-30-2
SmilesO=C1C(=COC=2C=C(O)C=C(O)C12)C=3C=CC=4OC(C=CC4C3O)(C)C
Relative Density.1.443 g/cm3 (Predicted)
Storage & Solubility Information
Storagekeep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 40 mg/mL (113.53 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.8382 mL14.1908 mL28.3817 mL141.9084 mL
5 mM0.5676 mL2.8382 mL5.6763 mL28.3817 mL
10 mM0.2838 mL1.4191 mL2.8382 mL14.1908 mL
20 mM0.1419 mL0.7095 mL1.4191 mL7.0954 mL
50 mM0.0568 mL0.2838 mL0.5676 mL2.8382 mL
100 mM0.0284 mL0.1419 mL0.2838 mL1.4191 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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