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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | LIN28-IN-1 (compound 5) is a selective inhibitor targeting the RNA-binding protein LIN28, specifically binding to its cold shock domain (CSD). This compound robustly interrupts the LIN28-let-7 miRNA interaction with an IC 50 of 5.4 μM, thereby mitigating LIN28's adverse effects on epigenetic gene control. Furthermore, LIN28-IN-1 exhibits significant anti-proliferative activity against LIN28-expressing JAR cancer cells, evidenced by an IC 50 value of 6.4 μM [1]. |
Cas No. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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