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LM-1484

Name: LM-1484
Brand: TargetMol
SKU: T11860
Rating: 4.5 (1 reviews)

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Catalog No. T11860Cas No. 197506-02-8

LM-1484 displays a higher affinity for 3H-LTC4 sites and is an antagonist of CysLT1 receptor.

LM-1484

😃Good

Catalog No. T11860Cas No. 197506-02-8

LM-1484 displays a higher affinity for 3H-LTC4 sites and is an antagonist of CysLT1 receptor.

Pack Size	Price	Availability
25 mg	$1,820	8-10 weeks
50 mg	$2,380	8-10 weeks
100 mg	$3,100	8-10 weeks

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Product Introduction

Bioactivity

Description	LM-1484 displays a higher affinity for 3H-LTC4 sites and is an antagonist of CysLT1 receptor.
In vitro	LM-1484 (10 μM) induces ³H-LTD₄ dissociation and displaces ³H-LTC₄ from its binding sites[1].

Chemical Properties

Molecular Weight	464.52
Formula	C₂₈H₂₄N₄O₃
Cas No.	197506-02-8
Relative Density.	1.309 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

LTC4LM-1484LM1484LM 1484CysLT1