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LSN3160440

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Catalog No. T75112Cas No. 2765539-59-9

LSN3160440 is an allosteric modulator of GLP-1R that functions as a protein-protein interaction (PPI) stabilizer or molecular glue, aiding in the binding of inactive GLP-1 (9-36) NH2 to GLP-1R, thereby enhancing receptor activation and potential therapeutic effects [1] [2].

LSN3160440

LSN3160440

😃Good
Catalog No. T75112Cas No. 2765539-59-9
LSN3160440 is an allosteric modulator of GLP-1R that functions as a protein-protein interaction (PPI) stabilizer or molecular glue, aiding in the binding of inactive GLP-1 (9-36) NH2 to GLP-1R, thereby enhancing receptor activation and potential therapeutic effects [1] [2].
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Product Introduction

Bioactivity
Description
LSN3160440 is an allosteric modulator of GLP-1R that functions as a protein-protein interaction (PPI) stabilizer or molecular glue, aiding in the binding of inactive GLP-1 (9-36) NH2 to GLP-1R, thereby enhancing receptor activation and potential therapeutic effects [1] [2].
Chemical Properties
Molecular Weight480.43
FormulaC27H27Cl2N3O
Cas No.2765539-59-9
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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