Shopping Cart

Remove All

Your shopping cart is currently empty

Lysine-specific Demethylase Inhibitor (1C) (hydrochloride)

Resource Download

Lysine-specific Demethylase Inhibitor (1C) (hydrochloride)

Catalog No. T36627Cas No. 1234494-75-7

Lysine-specific demethylase inhibitor (1C) (LSD inhibitor (1C)) is an inhibitor of LSD1, a repressive demethylase selective for histone H3 lysine 4 (H3K4).1,2LSD inhibitor (1C) inhibits LSD1 activity by 85.9% when used at a concentration of 10 μM.1It increases the level of H3K4 methylation, including H3K4me1 and H3K4me2 but not H3K9me2 levels, in HCT116 human colon carcinoma cells.2LSD inhibitor (1C) also induces re-expression of the Wnt signaling pathway proteins secreted frizzle-related protein 1 (SFRP1), SFRP4, and SFRP5, as well as the transcription factor GATA5, which are aberrantly silenced in HCT116 cells.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
1 mg	$52	Backorder
5 mg	$151	Backorder
10 mg	$250	Backorder

Bulk & Custom

Add to Cart

Questions

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	474.34
Formula	C15H40Cl4N8
Cas No.	1234494-75-7

Storage & Solubility Information

Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year
Solubility Information	DMSO: Soluble H2O: 50 mg/mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Lysine-specific Demethylase Inhibitor (1C)Lysinespecific Demethylase Inhibitor (1C) (hydrochloride)Lysine specific Demethylase Inhibitor (1C) (hydrochloride)

Related Tags: buy Lysine-specific Demethylase Inhibitor (1C) (hydrochloride) | purchase Lysine-specific Demethylase Inhibitor (1C) (hydrochloride) | Lysine-specific Demethylase Inhibitor (1C) (hydrochloride) cost | order Lysine-specific Demethylase Inhibitor (1C) (hydrochloride) | Lysine-specific Demethylase Inhibitor (1C) (hydrochloride) chemical structure | Lysine-specific Demethylase Inhibitor (1C) (hydrochloride) formula | Lysine-specific Demethylase Inhibitor (1C) (hydrochloride) molecular weight