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m-PEG6-O-CH2COOH is a PEG-based linker for PROTACs, facilitating the formation of PROTAC molecules by connecting two essential ligands. It enables selective protein degradation via the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | 7-10 days | |
500 mg | Inquiry | 7-10 days |
Description | m-PEG6-O-CH2COOH is a PEG-based linker for PROTACs, facilitating the formation of PROTAC molecules by connecting two essential ligands. It enables selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands linked together: one ligand binds to an E3 ubiquitin ligase and the other to a target protein. They utilize the intracellular ubiquitin-proteasome system for selective degradation of target proteins[1]. |
Molecular Weight | 354.39 |
Formula | C15H30O9 |
Cas No. | 75427-75-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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