Name: m-Cresol, 6-decyl-
Brand: TargetMol
SKU: T33234
Rating: 4.5 (1 reviews)

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100 mg

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500 mg

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QHow to use compounds in animal experiments? How to determine dosage and administrative routes?

AThe usage of the same compound may vary for different animal models and disease models. It is recommended to decide the usage based on the experimental purpose and refer to literatures. Common administration routes include intraperitoneal injection, oral gavage, etc. Due to the first-pass effect, compounds that can be administered orally may also be suitable for intraperitoneal injection, but those suitable for intraperitoneal injection may not necessarily be suitable for oral gavage. Dosages for different species can be converted based on tables provided on our official website. It is best to refer to specific literatures for dosages in a particular animal species. Our compounds can be used in both cell and animal experiments, but some compounds may not have literature supporting their use in animal experiments. In such cases, we cannot guarantee efficacy.

QWhat's the meaning of "< 1 mg/mL refers to the slightly soluble or insoluble"?

AIt means that if the solubility is less than 1 mg/mL

QWhy can't I see anything in the vial when I receive small-sized products?

ADue to the small pack, the powder may be highly dispersed during shipping due to static electricity and may adhere to the vial. Please centrifuge and add an appropriate solvent to fully dissolve the product and prepare the stock solution.

QWhat should I do if the IC50 obtained for cell killing are significantly different from that presented on the your website?

AThe IC50 you obtain refers to the cell proliferation inhibition assay (half maximal inhibitory concentration), which is different in meaning from the IC50 on our website. The IC50 often refers to the inhibition rate of the target without cell experiments, which is generally determined through kinase or protein purification experiments, and is commonly reported in nanomolar concentrations. However, the IC50 obtained from cell proliferation inhibition assays refers to the half-maximal lethality of the cells, which involves cellular metabolism and penetration, so the concentration is usually higher. Furthermore, the effect of the same compound on different cell models varies. It is recommended to try increasing the incubation volume and extending the incubation time.

QWhat is the calculation method for preparing a solution?

AThe calculation method is as follows: （1） c=n/v=m/M/v Concentration=amount of substance/volume=mass/molar mass/volume (2) The solution preparation table is presented in the the product details page on our website. You can add the volume of solvent as referenced.

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.