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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | m-PEG-NH2 (MW 10000) is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules. It enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands linked together: one binds to an E3 ubiquitin ligase, while the other targets a specific protein. These compounds utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Cas No. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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