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m-PEG-Tos (MW 2000) is a PEG-based linker utilized in PROTACs to join two essential ligands, facilitating the selective protein degradation through the ubiquitin-proteasome system within cells.
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Description | m-PEG-Tos (MW 2000) is a PEG-based linker utilized in PROTACs to join two essential ligands, facilitating the selective protein degradation through the ubiquitin-proteasome system within cells. |
In vitro | PROTACs, containing two distinct ligands linked by a connector—one for an E3 ubiquitin ligase and the other for the target protein—exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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