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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $34 | 5 days | |
50 mg | $47 | 5 days |
Description | m-PEG11-OH is a PEG-based linker for PROTACs, facilitating the joining of two essential ligands crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets the desired protein. These compounds leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Molecular Weight | 516.62 |
Formula | C23H48O12 |
Cas No. | 2168540-65-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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