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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $35 | 5 days | |
5 mg | $53 | 5 days | |
10 mg | $76 | 5 days |
Description | m-PEG12-Thiol is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands linked together: one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 576.74 |
Formula | C25H52O12S |
Cas No. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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