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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | m-PEG16-NH2 is a PEG-based linker essential for PROTACs, joining two key ligands to facilitate selective protein degradation through the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands joined by a linker: one targets an E3 ubiquitin ligase, while the other binds to the target protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 735.9 |
Formula | C33H69NO16 |
Cas No. | 907577-50-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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