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m-PEG2-Amino is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $32 | 5 days | |
5 mg | $48 | 5 days | |
10 mg | $70 | 5 days | |
25 mg | $113 | 5 days |
Description | m-PEG2-Amino is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs comprise two distinct ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other targeting the desired protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 135.1616 |
Formula | C5H13NO3 |
Cas No. | 54149-49-4 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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