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Description | m-PEG3-Aminooxy is a PEG-based linker for PROTACs that connects two essential ligands, playing a crucial role in forming PROTAC molecules and enabling selective protein degradation by utilizing the ubiquitin-proteasome system within cells. |
In vitro | PROTACs, consisting of two ligands connected by a linker—one binding to an E3 ubiquitin ligase and the other to the target protein—utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 179.21 |
Formula | C7H17NO4 |
Cas No. | 248275-10-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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