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m-PEG48-amine, a PEG-based linker for PROTACs, facilitates the formation of PROTAC molecules by connecting two essential ligands. This linker enables selective protein degradation via the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | m-PEG48-amine, a PEG-based linker for PROTACs, facilitates the formation of PROTAC molecules by connecting two essential ligands. This linker enables selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs feature two distinct ligands connected by a linker: one binds an E3 ubiquitin ligase and the other targets the specific protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 2145.6 |
Formula | C97H197NO48 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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