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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | 7-10 days | |
500 mg | Inquiry | 7-10 days |
Description | m-PEG5-SH is a PEG-based linker used in PROTACs, joining two critical ligands necessary for forming PROTAC molecules. This linker facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells. |
In vitro | PROTACs, incorporating two distinct ligands connected by a linker—one targeting an E3 ubiquitin ligase and the other the target protein—utilize the intracellular ubiquitin-proteasome system for selective protein degradation [1]. |
Molecular Weight | 268.37 |
Formula | C11H24O5S |
Cas No. | 524030-00-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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