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m-PEG6-thiol, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $43 | 5 days | |
10 mg | $61 | 5 days | |
25 mg | $98 | 5 days | |
50 mg | $143 | 5 days | |
100 mg | $239 | 5 days |
Description | m-PEG6-thiol, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands connected by a linker: one binds to an E3 ubiquitin ligase, and the other targets a specific protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Molecular Weight | 312.42 |
Formula | C13H28O6S |
Cas No. | 441771-60-4 |
Relative Density. | 1.057 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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