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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | m-PEG7-Tos is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker enhances selective protein degradation by utilizing the ubiquitin-proteasome system within cells. |
In vitro | PROTACs, comprising two distinct ligands—one binding to an E3 ubiquitin ligase and the other to the target protein—are linked by a connector. These compounds leverage the intracellular ubiquitin-proteasome system for the targeted degradation of specific proteins[1]. |
Molecular Weight | 494.6 |
Formula | C22H38O10S |
Cas No. | 79622-11-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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