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Mal-amino-sulfo is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | 1.444 € | Backorder |
Description | Mal-amino-sulfo is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs feature two distinct ligands linked together: one targets an E3 ubiquitin ligase, while the other targets the protein of interest. They harness the intracellular ubiquitin-proteasome system to specifically degrade target proteins[1]. |
Molecular Weight | 360.29 |
Formula | C12H12N2O9S |
Cas No. | 158018-81-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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