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Mal-C2-cyclohexylcarboxyl-hydrazide hydrochloride is an alkyl chain-based PROTAC linker commonly used in PROTAC synthesis.
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Description | Mal-C2-cyclohexylcarboxyl-hydrazide hydrochloride is an alkyl chain-based PROTAC linker commonly used in PROTAC synthesis. |
In vitro | PROTACs consist of two distinct ligands linked together: one binds to an E3 ubiquitin ligase, and the other to the target protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Alias | Mal-C2-cyclohexylcarboxyl-hydrazide hydrochloride |
Molecular Weight | 287.74 |
Formula | C12H18ClN3O3 |
Cas No. | 174422-72-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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