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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Mal-NH-PEG4-CH2CH2COOPFP ester, a polyethylene glycol (PEG) based linker, is used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1]. |
In vitro | PROTACs consist of two ligands linked together: one binding to an E3 ubiquitin ligase and the other to the target protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Molecular Weight | 582.47 |
Formula | C24H27F5N2O9 |
Cas No. | 1347750-84-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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