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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Mal-PEG8-alcohol is a PEG-based linker used in PROTACs, joining two essential ligands crucial for forming PROTAC molecules, and enabling selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands linked together: one targets an E3 ubiquitin ligase, and the other targets the specific protein. They harness the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Molecular Weight | 449.49 |
Formula | C20H35NO10 |
Cas No. | 2353409-63-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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