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Mavacamten-d6

Catalog No. TMID-0010Cas No. 2453251-18-6

Mavacamten-d6 is a deuterated compound of Mavacamten. Mavacamten has a CAS number of 1642288-47-8. MYK-461 is an orally bioavailable inhibitor of cardiac myosin ATPase,( IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively)

Mavacamten-d6
Other Forms of Mavacamten-d6:
MavacamtenT71341642288-47-8
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Mavacamten-d6

Catalog No. TMID-0010Cas No. 2453251-18-6
Mavacamten-d6 is a deuterated compound of Mavacamten. Mavacamten has a CAS number of 1642288-47-8. MYK-461 is an orally bioavailable inhibitor of cardiac myosin ATPase,( IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively)
Pack SizePriceAvailabilityQuantity
1 mg$4577-10 days
5 mg$1,3707-10 days
10 mg$2,2807-10 days
25 mg$4,2207-10 days
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Product Introduction

Bioactivity
Description
Mavacamten-d6 is a deuterated compound of Mavacamten. Mavacamten has a CAS number of 1642288-47-8. MYK-461 is an orally bioavailable inhibitor of cardiac myosin ATPase,( IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively)
Chemical Properties
Molecular Weight279.37
FormulaC15H13D6N3O2
Cas No.2453251-18-6
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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