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MBC-11

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Purity:100%

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COA HNMR PNMR HPLC

MBC-11

Catalog No. T11956LCas No. 332863-86-2

MBC-11 A coupling agent that targets cancer by concentrating cytarabine and etidronate at the site of disease.MBC-11 is used to study tumor-induced bone disease.

With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.

Pack Size	Price	Availability
1 mg	$293	In Stock
2 mg	$436	In Stock
5 mg	$722	In Stock
10 mg	$987	In Stock
25 mg	$1,520	In Stock
50 mg	$1,980	In Stock

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Product Introduction

Bioactivity

Description	MBC-11 A coupling agent that targets cancer by concentrating cytarabine and etidronate at the site of disease.MBC-11 is used to study tumor-induced bone disease.
In vitro	In human multiple myeloma cell lines (KAS-6/1, DP-6, KP-6), MBC-11 (0.1-100 µM) significantly inhibited multiple myeloma cell proliferation in each cell line at the majority of tested concentrations[1].
In vivo	In approximately four-week-old female Balb/c mice with a breast tumor model, MBC-11 (0.04, 0.4, or 4.0 μg/day; subcutaneous injection daily from day 7 to day 21) at a dose of 0.04 μg/day had a lower incidence of bone metastases compared to those treated with PBS or 0.04 μg/day zoledronate[1].

Chemical Properties

Molecular Weight	511.21
Formula	C11H20N3O14P3
Cas No.	332863-86-2

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

MBC 11MBC-11MBC11