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MC-1-F2

Name: MC-1-F2
Brand: TargetMol
SKU: T69659
Price: 1520 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T69659Cas No. 2376894-10-7

MC-1-F2 is a direct FOXC2 inhibitor with anticancer activity, inhibits cancer stem cell (CSC) characteristics, and reduces the invasive ability of castration-resistant prostate cancer (CRPC) cell lines. MC-1-F2 can be used to study prostate cancer.

MC-1-F2

Purity: 97.92%

Catalog No. T69659Cas No. 2376894-10-7

Pack Size	Price	Availability
25 mg	$1,520	In Stock
50 mg	$1,980	In Stock
100 mg	$2,500	In Stock

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Purity:97.92%

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COA HNMR HPLC LCMS

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	MC-1-F2 is a direct FOXC2 inhibitor with anticancer activity, inhibits cancer stem cell (CSC) characteristics, and reduces the invasive ability of castration-resistant prostate cancer (CRPC) cell lines. MC-1-F2 can be used to study prostate cancer.
In vitro	In PC3 or DU145 cell lines after treatment with DMSO (D), MC-1-F2 (F2, 20 µM) or MC-C2 (C, 20 µM) for 48 hours. A clear decrease in FOXC2 protein level upon 48-hour treatment with MC-1-F2. [1]

Chemical Properties

Molecular Weight	746.87
Formula	C₃₇H₄₆N₁₆O₂
Cas No.	2376894-10-7

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 80 mg/mL (107.11 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.3389 mL	6.6946 mL	13.3892 mL	66.9461 mL
5 mM	0.2678 mL	1.3389 mL	2.6778 mL	13.3892 mL
10 mM	0.1339 mL	0.6695 mL	1.3389 mL	6.6946 mL
20 mM	0.0669 mL	0.3347 mL	0.6695 mL	3.3473 mL
50 mM	0.0268 mL	0.1339 mL	0.2678 mL	1.3389 mL
100 mM	0.0134 mL	0.0669 mL	0.1339 mL	0.6695 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc