Shopping Cart
- Remove All
![TargetMol](https://www.targetmol.com/storage/error/oops.webp)
Your shopping cart is currently empty
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 μg | $390 | 35 days | |
25 μg | $923 | 35 days | |
50 μg | $1,740 | 35 days | |
100 μg | $2,900 | 35 days |
Description | Maresin conjugates in tissue regeneration 1 (MCTR1) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid in macrophages at the site of inflammation. DHA is oxidized to maresin 1 , which is then converted to MCTR1 by glutathione S-transferase Mu 4 or leukotriene C4 synthase. MCTR1 accelerates tissue regeneration in planaria (1 and 100 nM). Pretreatment with MCTR1 (50 ng/mouse, i.p.) prior to E. coli administration reduces neutrophil infiltration, shortens the inflammatory resolution period, and increases phagocytosis of E. coli by macrophages. When administered at a dose of 100 ng 12h post E. coli infection in a mouse model of peritonitis, MCTR1 reduces the amount of eicosanoids in the exudate. |
Alias | MCTR1 |
Molecular Weight | 649.8 |
Formula | C32H47N3O9S |
Cas No. | 1784701-61-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility Information | PBS (pH 7.2): 100 μg/mL Ethanol: 1 mg/mL DMF: 50 mg/mL DMSO: 50 mg/mL |
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.