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MEK/PI3K-IN-1

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Catalog No. T74360Cas No. 2281803-28-7

MEK/PI3K-IN-1 (compound 6r) is a potent dual inhibitor of MEK and PI3K, exhibiting IC50 values of 124 nM for MEK1, 130 nM for PI3Kα, and 236 nM for PI3Kδ. It effectively reduces pAKT and pERK1/2 levels, demonstrating anti-proliferative effects on various tumor cell lines [1].

MEK/PI3K-IN-1

MEK/PI3K-IN-1

😃Good
Catalog No. T74360Cas No. 2281803-28-7
MEK/PI3K-IN-1 (compound 6r) is a potent dual inhibitor of MEK and PI3K, exhibiting IC50 values of 124 nM for MEK1, 130 nM for PI3Kα, and 236 nM for PI3Kδ. It effectively reduces pAKT and pERK1/2 levels, demonstrating anti-proliferative effects on various tumor cell lines [1].
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Product Introduction

Bioactivity
Description
MEK/PI3K-IN-1 (compound 6r) is a potent dual inhibitor of MEK and PI3K, exhibiting IC50 values of 124 nM for MEK1, 130 nM for PI3Kα, and 236 nM for PI3Kδ. It effectively reduces pAKT and pERK1/2 levels, demonstrating anti-proliferative effects on various tumor cell lines [1].
Chemical Properties
Molecular Weight913.63
FormulaC36H37F5IN9O6
Cas No.2281803-28-7
Storage & Solubility Information
StorageShipping with blue ice.

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