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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | 6-8 weeks | |
50 mg | $1,980 | 6-8 weeks | |
100 mg | $2,500 | 6-8 weeks |
Description | Metallo-β-lactamase-IN-7 is a potent inhibitor of VIM -Type metallo-β-lactamase with IC 50 s of 0.019 μM, 13.64 μM, 0.38 μM for VIM-2, VIM-1 and VIM-5, respectively. Metallo-β-lactamase-IN-7 also enhances the antibacterial activity of Meropenem against the Gram-negative bacterial strains [1]. |
In vitro | Metallo-β-lactamase-IN-7 (compound 59) at a concentration of 10 μM over 18-20 hours enhances the effectiveness of Meropenem in combating VIM-2 mediated antibacterial resistance, as indicated by Fractional Inhibitory Concentration (FIC) index values of 0.02 [1]. At a higher concentration of 100 μM, it also increases Meropenem's antibacterial activity against PA W35, with FIC index values of 0.125 [1]. |
Molecular Weight | 274.3 |
Formula | C12H10N4O2S |
Cas No. | 2752453-58-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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