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Methyl-PEG2-alcohol, a PEG-based linker for PROTACs, joins two essential ligands necessary for forming PROTAC molecules and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | 7-10 days | |
500 mg | Inquiry | 7-10 days |
Description | Methyl-PEG2-alcohol, a PEG-based linker for PROTACs, joins two essential ligands necessary for forming PROTAC molecules and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands joined by a linker; one binds to an E3 ubiquitin ligase, and the other to the target protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Alias | Methyl-PEG2-alcohol |
Molecular Weight | 120.15 |
Formula | C5H12O3 |
Cas No. | 111-77-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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