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Methyltetrazine-acid

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Catalog No. T16055Cas No. 1380500-88-8

Methyltetrazine-acid is an alkyl chain-derived linker used for PROTAC synthesis [1].

Methyltetrazine-acid

Methyltetrazine-acid

😃Good
Catalog No. T16055Cas No. 1380500-88-8
Methyltetrazine-acid is an alkyl chain-derived linker used for PROTAC synthesis [1].
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500 mgInquiry7-10 days
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Product Introduction

Bioactivity
Description
Methyltetrazine-acid is an alkyl chain-derived linker used for PROTAC synthesis [1].
In vitro
PROTACs consist of two different ligands connected by a linker: one ligand binds to an E3 ubiquitin ligase, and the other binds to the target protein, facilitating the selective degradation of target proteins through the intracellular ubiquitin-proteasome system[1].
Chemical Properties
Molecular Weight230.22
FormulaC11H10N4O2
Cas No.1380500-88-8
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

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